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Volume 11, Issue 9, September 2019

Research Highlight

AFF3: a new player in maintaining XIST monoallelic expression
Reiner A. Veitia
J Mol Cell Biol, Volume 11, Issue 9, September 2019, 723-724, https://doi.org/10.1093/jmcb/mjy082
Abstract | Full Text 

Reviews

DCAF1 (VprBP): emerging physiological roles for a unique dual-service E3 ubiquitin ligase substrate receptor
N. Max Schabla , Koushik Mondal , and Patrick C. Swanson
J Mol Cell Biol, Volume 11, Issue 9, September 2019, 725-735, https://doi.org/10.1093/jmcb/mjy085
Abstract | Full Text 
News about non-secretory exocytosis: mechanisms, properties, and functions
Rosalba D’Alessandro and Jacopo Meldolesi
J Mol Cell Biol, Volume 11, Issue 9, September 2019, 736-746, https://doi.org/10.1093/jmcb/mjy084
Abstract | Full Text 

Articles

MicroRNA-24 promotes pancreatic beta cells toward dedifferentiation to avoid endoplasmic reticulum stress-induced apoptosis
Yunxia Zhu, Yi Sun, Yuncai Zhou, Yan Zhang, Tao Zhang, Yating Li, Weiyan You, Xiaoai Chang, Li Yuan, and Xiao Han *
J Mol Cell Biol, Volume 11, Issue 9, September 2019, 747-760, https://doi.org/10.1093/jmcb/mjz004
Abstract | Full Text 
AFF3-DNA methylation interplay in maintaining the mono-allelic expression pattern of XIST in terminally differentiated cells Free
Yue Zhang, Chao Wang, Xiaoxu Liu, Qian Yang, Hongliang Ji, Mengjun Yang, Manman Xu, Yunyan Zhou, Wei Xie , Zhuojuan Luo , and Chengqi Lin
J Mol Cell Biol, Volume 11, Issue 9, September 2019, 761-769, https://doi.org/10.1093/jmcb/mjy074
Abstract | Full Text 
Chlamydomonas WDR92 in association with R2TP-like complex and multiple DNAAFs to regulate ciliary dynein preassembly
Guang Liu, Limei Wang, and Junmin Pan
J Mol Cell Biol, Volume 11, Issue 9, September 2019, 770-780, https://doi.org/10.1093/jmcb/mjy067
Abstract | Full Text 
Rheb promotes brown fat thermogenesis by Notch-dependent activation of the PKA signaling pathway
Wen Meng , Xiuci Liang, Ting Xiao , Jing Wang , JieWen , Hairong Luo , Jianhui Teng, Yanquan Fei, Qinghai Zhang , Bilian Liu, Fang Hu, Juli Bai , Meilian Liu, Zhiguang Zhou , and Feng Liu
J Mol Cell Biol, Volume 11, Issue 9, September 2019, 781-790, https://doi.org/10.1093/jmcb/mjz056
Abstract | Full Text 
E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation Free
Weirong Jiang, Xia Yao, Zhaoliang Shan, Wenting Li, Yuxue Gao, and Qing Zhang
J Mol Cell Biol, Volume 11, Issue 9, September 2019, 791-803, https://doi.org/10.1093/jmcb/mjz024
Abstract | Full Text 

Letters to the Editor

HDAC-dependent decrease in histone crotonylation during DNA damage
Enas R. Abu-Zhayia , Feras E. Machour , and Nabieh Ayoub*
J Mol Cell Biol, Volume 11, Issue 9, September 2019, 804-806, https://doi.org/10.1093/jmcb/mjz019
Abstract | Full Text 
The C-terminal low-complexity domain involved in liquid–liquid phase separation is required for BRD4 function in vivo
Chenlu Wang, Erhao Zhang, FanWu , Yufeng Su, YingchengWu, Baorui Tao , Yue Ming, Yuanpei Xu, RenfangMao , and Yihui Fan
J Mol Cell Biol, Volume 11, Issue 9, September 2019, 807-809, https://doi.org/10.1093/jmcb/mjz037
Abstract | Full Text 

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Cover: Under metabolic burdens, the ER stress effector miR-24 is induced in pancreatic Β cells. The elevated miR-24 converts Β cells into a fetal state (dedifferentiation) to avoid programmed cell death (apoptosis), thus conserving the ‘fighting strength’. Once the metabolic burdens are remitted and the hyperglycemia is controlled, inhibition of miR-24 might be an attractive therapeutic approach to reviving functional Β cell number and treating diabetes. See pages 747–760 by Zhu et al. for details.