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Volume 11, Issue 11, November 2019

Research Highlight

Microtubule nucleation and dynamic instability in interphase fission yeast
Xin Liang
J Mol Cell Biol, Volume 11, Issue 11, November 2019, 941-943, https://doi.org/10.1093/jmcb/mjz044
Abstract | Full Text 

Articles

Alp7-Mto1 and Alp14 synergize to promote interphase microtubule regrowth from the nuclear envelope
Wenyue Liu , Fan Zheng , YucaiWang, and Chuanhai Fu
J Mol Cell Biol, Volume 11, Issue 11, November 2019, 944-955, https://doi.org/10.1093/jmcb/mjz038
Abstract | Full Text 
The concerted actions of Tip1/CLIP-170, Klp5/Kinesin-8, and Alp14/XMAP215 regulate microtubule catastrophe at the cell end
Xiaojia Niu , Fan Zheng , and Chuanhai Fu
J Mol Cell Biol, Volume 11, Issue 11, November 2019, 956-966, https://doi.org/10.1093/jmcb/mjz039
Abstract | Full Text 
Tubulin detyrosination promotes human trophoblast syncytium formation
Rui Wang , Ruoxuan Yu , Cheng Zhu, Hai-Yan Lin, Xiaoyin Lu , and Hongmei Wang
J Mol Cell Biol, Volume 11, Issue 11, November 2019, 967-978, https://doi.org/10.1093/jmcb/mjz084
Abstract | Full Text 
ADAM10 sheddase activation is controlled by cell membrane asymmetry
Florian Bleibaum, Anselm Sommer, Martin Veit, Bjo¨rn Rabe, Jo¨rg Andra¨, Karl Kunzelmann, Christian Nehls, Wilmar Correa, Thomas Gutsmann, Joachim Gro¨tzinger, Sucharit Bhakdi, and Karina Reiss
J Mol Cell Biol, Volume 11, Issue 11, November 2019, 979-993, https://doi.org/10.1093/jmcb/mjz008
Abstract | Full Text 
NUMB regulates the endocytosis and activity of the anaplastic lymphoma kinase in an isoform-specific manner
Ran Wei , Xuguang Liu , Courtney Voss, Wentao Qin, Lina Dagnino, Lei Li, Marc Vigny, and Shawn Shun-Cheng Li
J Mol Cell Biol, Volume 11, Issue 11, November 2019, 994-1005, https://doi.org/10.1093/jmcb/mjz003
Abstract | Full Text 
Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif
Thi Hai Yen Tran , Dae-Wook Yang, Minchul Kim, Da-Hye Lee, Marta Gai, Ferdinando Di Cunto, Kwang-Wook Choi, and Dae-Sik Lim
J Mol Cell Biol, Volume 11, Issue 11, November 2019, 1006-1017, https://doi.org/10.1093/jmcb/mjz013
Abstract | Full Text 

Application Note

Systematical study of the mechanistic factors regulating genome dynamics in vivo by CRISPRsie
Deqiang Han, Yu Hong , Xueying Mai, Qingtao Hu, Guangqing Lu, Jinzhi Duan, Jingru Xu, Xiaofang Si , and Yu Zhang
J Mol Cell Biol, Volume 11, Issue 11, November 2019, 1018-1020, https://doi.org/10.1093/jmcb/mjz074
Abstract | Full Text 
Transgenic strategies to generate heterogeneous hepatic cancer models in zebrafish
Fei Fei, LeiWang, Shaoyang Sun, Kunpeng Lv, Yuxiao Yao, Jingjing Wang, Min Yu, and Xu Wang
J Mol Cell Biol, Volume 11, Issue 11, November 2019, 1021-1023, https://doi.org/10.1093/jmcb/mjz083
Abstract | Full Text 

Research Advance

Comments on ‘Molecular architecture of lineage allocation and tissue organization in early mouse embryo’
Guizhong Cui, Naihe Jing , and Guangdun Peng
J Mol Cell Biol, Volume 11, Issue 11, November 2019, 1024-1025, https://doi.org/10.1093/jmcb/mjz101
Abstract | Full Text 

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Cover: Caption for cover image of JMCB 11-11 Post-translational modification of a-tubulin contributes to cell?cell fusion. Super-resolution microscopy reveals the diversity of microtubules in human placental trophoblast cells (total α-tubulin, green; detyrosinated α-tubulin, red). Detyrosinated a-tubulin is required for trophoblast fusion. Deficiency of α-tubulin detyrosination may contribute to the onset of pregnancy-related disease, like preeclampsia. See pages 967-978 by Wang et al. for details.