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Volume 13, Issue 6, June 2021

Articles

The septin complex links the catenin complex to the actin cytoskeleton for establishing epithelial cell polarity
Xueying Wang, Wenwen Wang, Xiwei Wang, Ming Wang, Lijuan Zhu, Fatima Garba, Chuanhai Fu, Barbara Zieger, Xu Liu, Xing Liu, Xuebiao Yao
J Mol Cell Biol, Volume 13, Issue 6, June 2021, 395-408, https://doi.org/10.1093/jmcb/mjab036
Abstract | Full Text 
OIP5-AS1 specifies p53-driven POX transcription regulated by TRPC6 in glioma
Wei Shao, Zhen-Yu Hao, Yi-Fei Chen, Jun Du, Qian He, Liang-Liang Ren, Yan Gao, Nan Song, Yan Song, Hua He, Yi-Zheng Wang
J Mol Cell Biol, Volume 13, Issue 6, June 2021, 409-421, https://doi.org/10.1093/jmcb/mjab001
Abstract | Full Text 
miR-130b inhibits proliferation and promotes differentiation in myocytes via targeting Sp1
Yu-Cheng Wang, Xiaohan Yao, Mei Ma, Huihui Zhang, Hui Wang, Lei Zhao, Shengnan Liu, Chao Sun, Peng Li, Yuting Wu, Xihua Li, Jingjing Jiang, Yuying Li, Yan Li, Hao Ying
J Mol Cell Biol, Volume 13, Issue 6, June 2021, 422-432, https://doi.org/10.1093/jmcb/mjab012
Abstract | Full Text 
Fatty acid oxidation and autophagy promote endoxifen resistance and counter the effect of AKT inhibition in ER-positive breast cancer cells
Lei Duan, Sarah Calhoun, Daeun Shim, Ricardo E. Perez, Lothar A. Blatter, Carl G. Maki
J Mol Cell Biol, Volume 13, Issue 6, June 2021, 433-444, https://doi.org/10.1093/jmcb/mjab018
Abstract | Full Text 
Cholesterol metabolic enzyme Ggpps regulates epicardium development and ventricular wall architecture integrity in mice
Feng Zheng, Zhong Chen, Qiao-Li Tang, Xin-Ying Wang, Dan-Yang Chong, Tong-Yu Zhang, Ya-Yun Gu, Zhi-Bin Hu, Chao-Jun Li
J Mol Cell Biol, Volume 13, Issue 6, June 2021, 445-454, https://doi.org/10.1093/jmcb/mjab019
Abstract | Full Text 

Application Note

Measurement of dynamic membrane mechanosensation using optical tweezers
Xuanling Li, Xing Liu, Xiaoyu Song, Yinmei Li, Ming Li, Haowei Wang
J Mol Cell Biol, Volume 13, Issue 6, June 2021, 455-457, https://doi.org/10.1093/jmcb/mjab021
Abstract | Full Text 

Research Advance

Comments on ‘MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche’
Ningbo Wu, Hongxiang Sun, Jianmei Tan, Yao Zhang, Bing Su
J Mol Cell Biol, Volume 13, Issue 6, June 2021, 458-459, https://doi.org/10.1093/jmcb/mjab026
Abstract | Full Text 
Hyocholic acid and glycemic regulation: comments on ‘Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism’
Wei Jia, Cynthia Rajani, Xiaojiao Zheng, Weiping Jia
J Mol Cell Biol, Volume 13, Issue 6, June 2021, 460-462, https://doi.org/10.1093/jmcb/mjab027
Abstract | Full Text 

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Cover: The cover image depicts a 3D mouse intestinal organoid labelled with F-actin (red) to mark apical membrane and septin7 (green) to annotate basolateral membranes. DNA is labelled in blue. This montage highlights that the polarity machinery is conserved from mouse to human and from simple 3D culture to complex cell lineage of organoids. Using real-time microscopic imaging, researchers show the development of 3D organoids in culture and the function of septin complex in epithelial cell polarity. See pages 395–408 by Wang et al. for details.