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Volume 14, Issue 3, March 2022

Research Highlight

A gating mechanism of K2P channels by their selectivity filter
Fan Yang
J Mol Cell Biol, Volume 14, Issue 3, March 2022, mjac018, https://doi.org/10.1093/jmcb/mjac018
Abstract | Full Text 

Review

Versatile functions of RNA m6A machinery on chromatin
Tanjing Song, Suli Lv, Neng Li, Xuefeng Zhao, Xianyun Ma, Yingying Yan, Weixia Wang, Lidong Sun
J Mol Cell Biol, Volume 14, Issue 3, March 2022, mjac011, https://doi.org/10.1093/jmcb/mjac011
Abstract | Full Text 

Articles

HDL quality features revealed by proteome‒lipidome connectivity are associated with atherosclerotic disease
Dandan Wang, Bilian Yu, Qingrun Li, Yanhong Guo, Tomonari Koike, Yui Koike, Qingqing Wu, Jifeng Zhang, Ling Mao, Xiaoyu Tang, Liang Sun, Xu Lin, Jiarui Wu, Y. Eugene Chen, Daoquan Peng, Rong Zeng
J Mol Cell Biol, Volume 14, Issue 3, March 2022, mjac004, https://doi.org/10.1093/jmcb/mjac004
Abstract | Full Text 
Incorporation of a histone mutant with H3K56 site substitution perturbs the replication machinery in mouse embryonic stem cells
Xuan Kang, Xiaomei Yang, Xiaobo Guo, Yabin Li, Chenxin Yang, Huimin Wei, jianfeng Chang
J Mol Cell Biol, Volume 14, Issue 3, March 2022, mjac014, https://doi.org/10.1093/jmcb/mjac014
Abstract | Full Text 
Regulation of the urea cycle by CPS1 O-GlcNAcylation in response to dietary restriction and aging
Jing Wu, Jiayu Liu, Kalina Lapenta, Reina Desrouleaux, Min-Dian Li, Xiaoyong Yang
J Mol Cell Biol, Volume 14, Issue 3, March 2022, mjac016, https://doi.org/10.1093/jmcb/mjac016
Abstract | Full Text 
Inner nuclear membrane protein TMEM201 maintains endothelial cell migration and angiogenesis by interacting with the LINC complex
Yutian Zhang, Ya Kong, Haoran Guo, Yun Liu, Yi Zang, Jia Li
J Mol Cell Biol, Volume 14, Issue 3, March 2022, mjac017, https://doi.org/10.1093/jmcb/mjac017
Abstract | Full Text 

Application Note

Synaptic degeneration in the prefrontal cortex of a rat AD model revealed by volume electron microscopy
Yi Jiang, Linlin Li, Keliang Pang, Jiazheng Liu, Bohao Chen, Jingbin Yuan, Lijun Shen, Xi Chen, Bai Lu, Hua Han
J Mol Cell Biol, Volume 14, Issue 3, March 2022, mjac012, https://doi.org/10.1093/jmcb/mjac012
Abstract | Full Text 

Corrigendum

Correction to ‘Landscape dynamic network biomarker analysis reveals the tipping point of transcriptome reprogramming to prevent skin photodamage’
Chengming Zhang, Hong Zhang, Jing Ge, Tingyan Mi, Xiao Cui, Fengjuan Tu, Xuelan Gu, Tao Zeng, Luonan Chen
J Mol Cell Biol, Volume 14, Issue 3, March 2022, mjac013, https://doi.org/10.1093/jmcb/mjac013
Abstract | Full Text 

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Cover: Molecular mechanisms of the ageing biology provide insights into proactive health and healthy aging. Are we getting close to the Fountain of Youth? O-GlcNAc may be one of the key molecules. Recently, it has been demonstrated that O-GlcNAcylation on the gate-keeper enzyme of the urea cycle, i.e. CPS1, is modulatory during ageing and reversible by dietary restriction. This image was contributed by Lihua Li (Southwest Hospital, Army Medical University). See mjac016 by Wu et al. for details.