Volume 5, Issue 6, December 2013

Editorial

Cell signaling for pathological responses Free
Jiarui Wu
J Mol Cell Biol, Volume 5, Issue 6, December 2013, 357-357, https://doi.org/10.1093/jmcb/mjt040
Abstract | Full Text 

Articles

Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells Free
Thomas Gruber, Reinhard Hinterleitner, Natascha Hermann-Kleiter, Marlies Meisel, Ingo Kleiter, Chiuhui Mary Wang, Antonella Viola, Christa Pfeifhofer-Obermair, and Gottfried Baier
J Mol Cell Biol, Volume 5, Issue 6, December 2013, 358-368, https://doi.org/10.1093/jmcb/mjt017
Abstract | Full Text 
Restoration of intrahepatic regulatory T cells through MMP-9/13-dependent activation of TGF-β is critical for immune homeostasis following acute liver injury Free
Ling Lu, Min Feng, Jia Gu, Zanxian Xia, Hongjun Zhang, Sujun Zheng, Zhongping Duan, Richard Hu, Julie Wang, Wei Shi, Cheng Ji, Yi Shen, Guihua Chen, Song Guo Zheng, and Yuan-Ping Han
J Mol Cell Biol, Volume 5, Issue 6, December 2013, 369-379, https://doi.org/10.1093/jmcb/mjt042
Abstract | Full Text 
Thromboxane A2 receptor α promotes tumor growth through an autoregulatory feedback pathway Free
Run-Yue Huang, Ming-Yue Li, Calvin S.H. Ng, Innes Y.P. Wan, Angel W.Y. Kong, Jing Du, Xiang Long, Malcolm J. Underwood, Tony S.K. Mok, and George G. Chen
J Mol Cell Biol, Volume 5, Issue 6, December 2013, 380-390, https://doi.org/10.1093/jmcb/mjt038
Abstract | Full Text 
E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B Free
David Engelmann, Deborah Mayoli-Nüssle, Christian Mayrhofer, Katharina Fürst, Vijay Alla, Anja Stoll, Alf Spitschak, Kerstin Abshagen, Brigitte Vollmar, Sophia Ran, and Brigitte M. Pützer
J Mol Cell Biol, Volume 5, Issue 6, December 2013, 391-403, https://doi.org/10.1093/jmcb/mjt035
Abstract | Full Text 
A specific cholesterol metabolic pathway is established in a subset of HCCs for tumor growth Free
Ming Lu, Xi-Han Hu, Qin Li, Ying Xiong, Guang-Jing Hu, Jia-Jia Xu, Xiao-Nan Zhao, Xi-Xiao Wei, Catherine C.Y. Chang, Yin-Kun Liu, Fa-Jun Nan, Jia Li, Ta-Yuan Chang, Bao-Liang Song, and Bo-Liang Li
J Mol Cell Biol, Volume 5, Issue 6, December 2013, 404-415, https://doi.org/10.1093/jmcb/mjt039
Abstract | Full Text 
A role for paralog-specific sumoylation in histone deacetylase 1 stability Free
Simona Citro, Ellis Jaffray, Ronald T. Hay, Christian Seiser, and Susanna Chiocca
J Mol Cell Biol, Volume 5, Issue 6, December 2013, 416-427, https://doi.org/10.1093/jmcb/mjt032
Abstract | Full Text 

Letter to the Editor

Inhibition of breast cancer local relapse by targeting p70S6 kinase activity Free
Ilenia Segatto, Stefania Berton, Maura Sonego, Samuele Massarut, Sara D'Andrea, Tiziana Perin, Linda Fabris, Joshua Armenia, Gianluca Rampioni, Sara Lovisa, Monica Schiappacassi, Alfonso Colombatti, Robert G. Bristow, Andrea Vecchione, Gustavo Baldassarre, and Barbara Belletti
J Mol Cell Biol, Volume 5, Issue 6, December 2013, 428-431, https://doi.org/10.1093/jmcb/mjt027
Abstract | Full Text 

Research Highlight

miR-133 links to energy balance through targeting Prdm16 Free
Weiyi Liu and Shihuan Kuang
J Mol Cell Biol, Volume 5, Issue 6, December 2013, 432-434, https://doi.org/10.1093/jmcb/mjt036
Abstract | Full Text 
Cover: Confocal immunofluorescence images of human CD4+ T cells. Cbl-b, a negative regulator of T cell activation, and SMAD7, an inhibitor of TGFβ signaling, co-localize in both cytosol and nucleus (Cbl-b, green; SMAD7, red; merged, yellow; nucleus, blue). The colocalization slightly but significantly increased after TGFβ stimulation (left, Control; right, 60/ TGFβ). See pages 358–368 by Gruber et al. for details.