Volume 6, Issue 5, October 2014

Editorial

Novel factors for cell differentiation and reprogramming Free
Jiarui Wu, Editor-in-Chief
J Mol Cell Biol, Volume 6, Issue 5, October 2014, Pages 355-355, https://doi.org/10.1093/jmcb/mju035
Abstract | Full Text 

Review

Epigenetics of human melanoma: promises and challenges Free
Ahmad Besaratinia and Stella Tommasi
J Mol Cell Biol, Volume 6, Issue 5, October 2014, Pages 356-367, https://doi.org/10.1093/jmcb/mju027
Abstract | Full Text 

Articles

CKIP-1 suppresses the adipogenesis of mesenchymal stem cells by enhancing HDAC1-associated repression of C/EBPα Free
Dahu Li, Heng Zhu, Chao Liang, Wenbo Li, Guichun Xing, Lanzhi Ma, Lujing Ding, Yi Zhang, Fuchu He, and Lingqiang Zhang
J Mol Cell Biol, Volume 6, Issue 5, October 2014, Pages 368-379, https://doi.org/10.1093/jmcb/mju034
Abstract | Full Text 
Monocyte-secreted Wnt5a interacts with FZD5 in microvascular endothelial cells and induces angiogenesis through tissue factor signaling Free
Gemma Arderiu, Sonia Espinosa, Esther Peña, Rosa Aledo, and Lina Badimon
J Mol Cell Biol, Volume 6, Issue 5, October 2014, Pages 380-393, https://doi.org/10.1093/jmcb/mju036
Abstract | Full Text 
Generation of insulin-producing β-like cells from human iPS cells in a defined and completely xeno-free culture system Free
Hussain Md. Shahjalal, Nobuaki Shiraki, Daisuke Sakano, Kazuhide Kikawa, Soichiro Ogaki, Hideo Baba, Kazuhiko Kume, and Shoen Kume
J Mol Cell Biol, Volume 6, Issue 5, October 2014, Pages 394-408, https://doi.org/10.1093/jmcb/mju029
Abstract | Full Text 
Small molecule compound induces chromatin de-condensation and facilitates induced pluripotent stem cell generation Free
Xiaoyuan Wei, Yueting Chen, Yongyu Xu, Yang Zhan, Ru Zhang, Min Wang, Qiuhong Hua, Haifeng Gu, Fajun Nan, and Xin Xie
J Mol Cell Biol, Volume 6, Issue 5, October 2014, Pages 409-420, https://doi.org/10.1093/jmcb/mju024
Abstract | Full Text 
De novo identification and quantification of single amino-acid variants in human brain Free
Zhi-Duan Su, Quan-Hu Sheng, Qing-Run Li, Hao Chi, Xi Jiang, Zheng Yan, Ning Fu, Si-Min He, Philipp Khaitovich, Jia-Rui Wu, and Rong Zeng
J Mol Cell Biol, Volume 6, Issue 5, October 2014, Pages 421-433, https://doi.org/10.1093/jmcb/mju031
Abstract | Full Text 

Letters to the Editor

RIM2α is a molecular scaffold for Zona pellucida-induced acrosome reaction Free
Nele Weber, Laura Vieweg, Franziska Henze, Ana-Maria Oprisoreanu, Hans Jürgen Solinski, Andreas Breit, Claudia Fecher-Trost, Pascal Schalkowsky, Beate Wilhelm, Gunther Wennemuth, Susanne Schoch, Thomas Gudermann, and Ingrid Boekhoff
J Mol Cell Biol, Volume 6, Issue 5, October 2014, Pages 434-437, https://doi.org/10.1093/jmcb/mju037
Abstract | Full Text 
High-accuracy mapping of protein binding stability on nucleosomal DNA using a single-molecule method Free
Jianshi Jin, Tengfei Lian, X. Sunney Xie, and Xiao-Dong Su
J Mol Cell Biol, Volume 6, Issue 5, October 2014, Pages 438-440, https://doi.org/10.1093/jmcb/mju033
Abstract | Full Text 
Cover: The PH domain-containing protein CKIP-1 is defined as a novel inhibitor of mesenchymal stem cell (MSC) adipogenesis, in which CKIP-1 enhances HDAC1-associated repression of C/EBPα and suppresses adipogenic differentiation of MSCs. Correspondingly, CKIP-1-deficientMSCs display increased C/EBPα expression and more adipocytes after induction. The background shows H&E staining of inguinal adipose tissue from CKIP-1 WT mice on regular diet. See pages 368–379 by Li et al. for details.