Volume 8, Issue 2, April 2016

Editorial

Reviews

Adiponectin, the past two decades Free
Zhao V. Wang, and Philipp E. Scherer
J Mol Cell Biol, Volume 8, Issue 2, April 2016, Pages 93-100, https://doi.org/10.1093/jmcb/mjw011
Abstract | Full Text 
Adiponectin signaling and function in insulin target tissues
Hong Ruan, and Lily Q. Dong
J Mol Cell Biol, Volume 8, Issue 2, April 2016, Pages 101-109, https://doi.org/10.1093/jmcb/mjw014
Abstract | Full Text 
The FGF21–adiponectin axis in controlling energy and vascular homeostasis Free
Xiaoyan Hui, Tianshi Feng, Qing Liu, Yuan Gao, and Aimin Xu
J Mol Cell Biol, Volume 8, Issue 2, April 2016, Pages 110-119, https://doi.org/10.1093/jmcb/mjw013
Abstract | Full Text 
Adiponectin: a versatile player of innate immunity Free
Yan Luo, and Meilian Liu
J Mol Cell Biol, Volume 8, Issue 2, April 2016, Pages 120-128, https://doi.org/10.1093/jmcb/mjw012
Abstract | Full Text 

Articles

Mitochondria-associated endoplasmic reticulum membranes allow adaptation of mitochondrial metabolism to glucose availability in the liver Free
Pierre Theurey, Emily Tubbs, Guillaume Vial, Julien Jacquemetton, Nadia Bendridi, Marie-Agnès Chauvin, Muhammad Rizwan Alam, Muriel Le Romancer, Hubert Vidal, and Jennifer Rieusset
J Mol Cell Biol, Volume 8, Issue 2, April 2016, Pages 129-143, https://doi.org/10.1093/jmcb/mjw004
Abstract | Full Text 
IRE1–RACK1 axis orchestrates ER stress preconditioning-elicited cytoprotection from ischemia/reperfusion injury in liver Free
Dong Liu, Xing Liu, Ti Zhou, William Yao, Jun Zhao, Zhigang Zheng, Wei Jiang, Fengsong Wang, Felix O. Aikhionbare, Donald L. Hill, Nerimah Emmett, Zhen Guo, Dongmei Wang, Xuebiao Yao, and Yong Chen
J Mol Cell Biol, Volume 8, Issue 2, April 2016, Pages 144-156, https://doi.org/10.1093/jmcb/mjv066
Abstract | Full Text 
In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases
Grigori Singovski, Carolina Bernal, Monika Kuciak, Irene Siegl-Cachedenier, Arwen Conod, and Ariel Ruiz i Altaba
J Mol Cell Biol, Volume 8, Issue 2, April 2016, Pages 157-173, https://doi.org/10.1093/jmcb/mjv034
Abstract | Full Text 

Letters to the Editor

Genetically humanized pigs exclusively expressing human insulin are generated through custom endonuclease-mediated seamless engineering Free
Yi Yang, Kepin Wang, Han Wu, Qin Jin, Degong Ruan, Zhen Ouyang, Bentian Zhao, Zhaoming Liu, Yu Zhao, Quanjun Zhang, Nana Fan, Qishuai Liu, Shimei Guo, Lei Bu, Yong Fan, Xiaofang Sun, Xiaoping Li, and Liangxue Lai
J Mol Cell Biol, Volume 8, Issue 2, April 2016, Pages 174-177, https://doi.org/10.1093/jmcb/mjw008
Abstract | Full Text 
Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity Free
Martina Gast, Blanche Schroen, Antje Voigt, Jan Haas, Uwe Kuehl, Dirk Lassner, Carsten Skurk, Felicitas Escher, Xiaomin Wang, Adelheid Kratzer, Katharina Michalik, Anna Papageorgiou, Tim Peters, Madlen Loebel, Sabrina Wilk, Nadine Althof, Kannanganattu V. Prasanth, Hugo Katus, Benjamin Meder, Shinichi Nakagawa11, Carmen Scheibenbogen8,9, Heinz-Peter Schultheiss, Ulf Landmesser, Stefanie Dimmeler, Stephane Heymans, and Wolfgang Poller
J Mol Cell Biol, Volume 8, Issue 2, April 2016, Pages 178-181, https://doi.org/10.1093/jmcb/mjw003
Abstract | Full Text 
Cover: Adiponectin improves overall insulin sensitivity and maintains energy homeostasis by various mechanisms, including direct and indirect improvement of insulin responsiveness in major insulin targets, suppression of inflammation and oxidative stress, and promotion of β cell survival. The altered secretory profiles of adiponectin targets, including adipokines, myokines, and hepatokines, and immune cell-derived factors mediate the indirect effects of adiponectin, thereby amplifying its insulinsensitizing activities. The extent to which these different mechanisms operate depends on cell type and physiological and pathophysiological settings. See pages 91–92 by Ruan and Liu for details.