Volume 10, Issue 1, February 2018

Editorial

New insights into the regulation of cell cycle Free
Jiarui Wu
J Mol Cell Biol, Volume 10, Issue 1, February 2018, Pages 1-1, https://doi.org/10.1093/jmcb/mjy015
Abstract | Full Text 

Articles

AMPK regulates anaphase central spindle length by phosphorylation of KIF4A Free
Qian-Ru Li , Xiu-Min Yan , Lin Guo , Jia Li , and Yi Zang
J Mol Cell Biol, Volume 10, Issue 1, February 2018, Pages 2-17, https://doi.org/10.1093/jmcb/mjx029
Abstract | Full Text 
Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation
Xiaoling Bao 1,† , Heng Liu 1,† , Xing Liu 2 , Ke Ruan 1 , Yonghui Zhang 1 , Zhiyong Zhang , Qi Hu , Ying Liu , Saima Akram , Jiahai Zhang , Qingguo Gong , Wenwen Wang , Xiao Yuan , Jian Li ,Lingli Zhao , Zhen Dou , Ruijun Tian , Xuebiao Yao, Jihui Wu , and Yunyu Shi
J Mol Cell Biol, Volume 10, Issue 1, February 2018, Pages 18-32, https://doi.org/10.1093/jmcb/mjx045
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TFIIA transcriptional activity is controlled by a ‘cleave-and-run’ Exportin-1/Taspase 1-switch Free
Christian Schrenk , Verena Fetz , Cecilia Vallet , Christina Heiselmayer , Elisabeth Schro ¨der , Astrid Hensel, Angelina Hahlbrock , De´sire´e Wu ¨nsch , Dorothee Goesswein , Carolin Bier , Negusse Habtemichael , Gu ¨nter Schneider , Roland H. Stauber , and Shirley K. Knauer
J Mol Cell Biol, Volume 10, Issue 1, February 2018, Pages 33-47, https://doi.org/10.1093/jmcb/mjx025
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CXXC5 suppresses hepatocellular carcinoma by promoting TGF-β-induced cell cycle arrest and apoptosis Free
Xiaohua Yan , , Jingyi Wu , Quanlong Jiang , Hao Cheng , Jing-Dong J. Han , and Ye-Guang Chen
J Mol Cell Biol, Volume 10, Issue 1, February 2018, Pages 48-59, https://doi.org/10.1093/jmcb/mjx042
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Phosphorylated E2F1 is stabilized by nuclear USP11 to drive Peg10 gene expression and activate lung epithelial cells Free
Dan Wang, Jing Zhao , Shuang Li , Jianxin Wei , Ling Nan , Rama K. Mallampalli , Nathaniel M. Weathington , Haichun Ma , and Yutong Zhao
J Mol Cell Biol, Volume 10, Issue 1, February 2018, Pages 60-73, https://doi.org/10.1093/jmcb/mjx034
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Zbed3 participates in the subcortical maternal complex and regulates the distribution of organelles Free
Zheng Gao , Xiaoxin Zhang , Xingjiang Yu , Dandan Qin , Yi Xiao , Yang Yu , Yunlong Xiang ,Xiaoqing Nie , Xukun Lu , Wenbo Liu, Zhaohong Yi , and Lei Li
J Mol Cell Biol, Volume 10, Issue 1, February 2018, Pages 74-88, https://doi.org/10.1093/jmcb/mjx035
Abstract | Full Text 

Research Highlight

Partner switching for Ran during the mitosis dance Free
Yang Yang , Hongtao Yu
J Mol Cell Biol, Volume 10, Issue 1, February 2018, Pages 89-90, https://doi.org/10.1093/jmcb/mjx048
Abstract | Full Text 
Cover: AMPK activity controls central spindle length. In normal condition (middle), KIF4A ATPase activity is modulated by balancing Aurora B (blue)- and AMPK (red)-dependent phosphorylation to construct a central spindle with appropriate size. Inhibiting AMPK activity or AMPK depletion induces an excess of Aurora B-dependent phosphorylation of KIF4A, which prematurely blocks central spindle elongation and shortens the central spindle length (left). In contrast, augmenting AMPK activity increases the competitiveness of AMPK-dependent phosphorylation and induces an undisturbed but elongated central spindle (right). See pages 2–17 by Li et al. for details.