Volume 11, Issue 7, July 2019

Editorial

Legends of p53: untold four-decade stories
Editor-in-Chief Hua Lu
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 521-522, https://doi.org/10.1093/jmcb/mjz079
Abstract | Full Text 
What’s knowledge is prologue: celebrating the 40th anniversary of the p53 discovery
Editor-in-Chief Jiarui Wu
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 523-523, https://doi.org/10.1093/jmcb/mjz064
Abstract | Full Text 

Perspective

The many faces of p53: something for everyone
Arnold J. Levine*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 524-530, https://doi.org/10.1093/jmcb/mjz026
Abstract | Full Text 

Retrospect

How TP53 (almost) became an oncogene
Robert A. Weinberg*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 531-533, https://doi.org/10.1093/jmcb/mjz061
Abstract | Full Text 
The Levine laboratory and the discovery of p53
Daniel Linzer*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 534-535, https://doi.org/10.1093/jmcb/mjz027
Abstract | Full Text 
p53: a tumor suppressor hiding in plain sight
Suzanne J. Baker and Bert Vogelstein
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 536-538, https://doi.org/10.1093/jmcb/mjz068
Abstract | Full Text 
p53: not just a tumor suppressor
Moshe Oren*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 539-543, https://doi.org/10.1093/jmcb/mjz070
Abstract | Full Text 
A paean to Arnie Levine on the occasion of his 80th birthday
Philip W. Hinds*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 544-545, https://doi.org/10.1093/jmcb/mjz066
Abstract | Full Text 
Arnold J. Levine and my career development
Yigong Shi*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 546-550, https://doi.org/10.1093/jmcb/mjz069
Abstract | Full Text 
Lessons from the lab: what I learned from Arnie Levine
Deborah Freedman-Cass*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 551-552, https://doi.org/10.1093/jmcb/mjz062
Abstract | Full Text 

Reviews

p53 balances between tissue hierarchy and anarchy
Gabriela Koifman, Ronit Aloni-Grinstein , and Varda Rotter
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 553-563, https://doi.org/10.1093/jmcb/mjz022
Abstract | Full Text 
p53 modifications: exquisite decorations of the powerful guardian
Yanqing Liu, Omid Tavana, and Wei Gu
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 564-577, https://doi.org/10.1093/jmcb/mjz060
Abstract | Full Text 
Common genetic variants in the TP53 pathway and their impact on cancer
Thibaut Barnoud, Joshua L. D. Parris , and Maureen E. Murphy
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 578-585, https://doi.org/10.1093/jmcb/mjz052
Abstract | Full Text 
Inhibition of p53 inhibitors: progress, challenges and perspectives
Gema Sanz, Madhurendra Singh, Sylvain Peuget, and Galina Selivanova*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 586-599, https://doi.org/10.1093/jmcb/mjz075
Abstract | Full Text 

Perspective

Mutant p53—a potential player in shaping the tumor–stroma crosstalk
Yan Stein, Ronit Aloni-Grinstein , and Varda Rotter
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 600-604, https://doi.org/10.1093/jmcb/mjz071
Abstract | Full Text 
Gain-of-function mutant p53: history and speculation
Jill Bargonetti and Carol Prives
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 605-609, https://doi.org/10.1093/jmcb/mjz067
Abstract | Full Text 
Taking up the reins of power: metabolic functions of p53
Timothy Humpton and Karen H. Vousden
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 610-614, https://doi.org/10.1093/jmcb/mjz065
Abstract | Full Text 
Restoring p53 in cancer: the promises and the challenges
Guillermina Lozano*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 615-619, https://doi.org/10.1093/jmcb/mjz063
Abstract | Full Text 
Arnie Levine and the MDM2–p53 discovery: a postdoctoral fellow’s perspective
Gerard P. Zambetti*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 620-623, https://doi.org/10.1093/jmcb/mjz073
Abstract | Full Text 
The role of p53 in reproduction, an unexpected function for a tumor suppressor
Wenwei Hu* and Zhaohui Feng*
J Mol Cell Biol, Volume 11, Issue 7, July 2019, Pages 624-627, https://doi.org/10.1093/jmcb/mjz072
Abstract | Full Text 

Meeting Report

Cover: The cover image p53 on top of Mount St. Helen in sky metaphorically illustrates the year of 1979 when the p53 airship was launched, which coincidentally was a year ahead of the 1980 volcanic eruption of Mount St. Helen that resides by the Columbia River in Skamania County, Washington, USA. This image also emblematically depicts how p53 acts via interaction with spring-like nuclear chromatin structures, but the whole picture of its functions in protecting human from cancer remains unfinished and mysteriously sky high still beyond the full reach of human scientists on earth, although tremendous progresses have been made to understand p53. The image was contributed by Timothy Z. Lu. See pages 521–522 by Lu for details.