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Volume 14, Issue 7, July 2022

Review

β-cell dynamics in type 2 diabetes and in dietary and exercise interventions
Chengan Lv, Yuchen Sun, Zhe Yu Zhang, Zeyad Aboelela, Xinyuan Qiu, Zhuo-Xian Meng
J Mol Cell Biol, Volume 14, Issue 7, July 2022, mjac046, https://doi.org/10.1093/jmcb/mjac046
Abstract | Full Text 

Articles

Tyrosine phosphatase SHP2 in ovarian granulosa cells balances follicular development by inhibiting PI3K/AKT signaling
Xiaoli Wei, Lanping Zheng, Yingpu Tian, Haibin Wang, Youqiang Su, Gensheng Feng, Chao Wang, Zhongxian Lu
J Mol Cell Biol, Volume 14, Issue 7, July 2022, mjac048, https://doi.org/10.1093/jmcb/mjac048
Abstract | Full Text 
Cilia regulate meiotic recombination in zebrafish
Haibo Xie, Xiaosi Wang, Minjun Jin, Lanqin Li, Junwen Zhu, Yunsi Kang, Zhe Chen, Yonghua Sun, Chengtian Zhao
J Mol Cell Biol, Volume 14, Issue 7, July 2022, mjac049, https://doi.org/10.1093/jmcb/mjac049
Abstract | Full Text 
CaMK4 overexpression in polycystic kidney disease promotes mTOR-mediated cell proliferation
Yan Zhang, Emily A. Daniel, July Metcalf, Yuqiao Dai, Gail A. Reif, Darren P. Wallace
J Mol Cell Biol, Volume 14, Issue 7, July 2022, mjac050, https://doi.org/10.1093/jmcb/mjac050
Abstract | Full Text 
Phosphorylation of CENP-R by Aurora B regulates kinetochore–microtubule attachment for accurate chromosome segregation
Divine Mensah Sedzro, Xiao Yuan, McKay Mullen, Umer Ejaz, Tongtong Yang, Xu Liu, Xiaoyu Song, Yun-Chi Tang, Weijun Pan, Peng Zou, Xinjiao Gao, Dongmei Wang, Zhikai Wang, Zhen Dou, Xing Liu, Xuebiao Yao
J Mol Cell Biol, Volume 14, Issue 7, July 2022, mjac051, https://doi.org/10.1093/jmcb/mjac051
Abstract | Full Text 

Research Advance

Comments on ‘Dietary intervention preserves β cell function in mice through CTCF-mediated transcriptional reprogramming’
Ruo-Ran Wang, Hongxing Fu, Jingya Li, Zhuo-Xian Meng
J Mol Cell Biol, Volume 14, Issue 7, July 2022, mjac043, https://doi.org/10.1093/jmcb/mjac043
Abstract | Full Text 
Polarized condensates confer row identity of hair cell stereocilia
Yingdong Shi, Lin Lin, Chao Wang, Jinwei Zhu
J Mol Cell Biol, Volume 14, Issue 7, July 2022, mjac045, https://doi.org/10.1093/jmcb/mjac045
Abstract | Full Text 

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Cover: A recent work delineated a dynamic map of β cell function and gene expression profiles during the onset and development of obesity and T2D. The study also revealed that dietary intervention preserves β cell function in mice through CTCF-mediated transcriptional reprogramming. This image schematically illustrates the effect of dietary factors on chromatin accessibility and transcriptome (outline of a rope: DNA strand) in β cells (shown by the humanized islet). See mjac043 by Wang et al. for details.