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Volume 15, Issue 4, April 2023

Articles

The actin-bundling protein Fascin-1 modulates ciliary signalling
Lena Brücker, Stefanie Kornelia Becker, Vanessa Maissl, Gregory Harms, Maddy Parsons, Helen Louise May-Simera
J Mol Cell Biol, Volume 15, Issue 4, April 2023, mjad022, https://doi.org/10.1093/jmcb/mjad022
Abstract | Full Text 
Accurate prediction of pan-cancer types using machine learning with minimal number of DNA methylation sites
Wei Ning, Tao Wu, Chenxu Wu, Shixiang Wang, Ziyu Tao, Guangshuai Wang, Xiangyu Zhao, Kaixuan Diao, Jinyu Wang, Jing Chen, Fuxiang Chen, Xue-Song Liu
J Mol Cell Biol, Volume 15, Issue 4, April 2023, mjad023, https://doi.org/10.1093/jmcb/mjad023
Abstract | Full Text 
CSF2 upregulates CXCL3 expression in adipocytes to promote metastasis of breast cancer via the FAK signaling pathway
Xi He, Lieliang Wang, Honghui Li, Yaru Liu, Chang Tong, Caifeng Xie, Xiaohua Yan, Daya Luo, Xiangyang Xiong
J Mol Cell Biol, Volume 15, Issue 4, April 2023, mjad025, https://doi.org/10.1093/jmcb/mjad025
Abstract | Full Text 
Human galectin-9 potently enhances SARS-CoV-2 replication and inflammation in airway epithelial cells
Li Du, Mohamed S. Bouzidi, Akshay Gala, Fred Deiter, Jean-Noël Billaud, Stephen T. Yeung, Prerna Dabral, Jing Jin, Graham Simmons, Zain Y. Dossani, Toshiro Niki, Lishomwa C. Ndhlovu, John R. Greenland, Satish K. Pillai
J Mol Cell Biol, Volume 15, Issue 4, April 2023, mjad030, https://doi.org/10.1093/jmcb/mjad030
Abstract | Full Text 

Letters to the Editor

SARS-CoV-2 main protease Nsp5 cleaves and inactivates human tRNA methyltransferase TRMT1
Jia-Li Lu, Xiao-Long Zhou
J Mol Cell Biol, Volume 15, Issue 4, April 2023, mjad024, https://doi.org/10.1093/jmcb/mjad024
Abstract | Full Text 
CMT2D neuropathy is influenced by vitamin D-mediated environmental pathway
Huaqing Liu, Mingmin Tang, Hualin Yu, Tongfei Liu, Qinqin Cui, Linfan Gu, Zhi-Ying Wu, Nengyin Sheng, Xiang-Lei Yang, Linghui Zeng, Ge Bai
J Mol Cell Biol, Volume 15, Issue 4, April 2023, mjad029, https://doi.org/10.1093/jmcb/mjad029
Abstract | Full Text 

Research Advance

Comments on ‘Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1–AMPK–LKB1 complex’
Sijia Lu, Suzhen Chen, Ji Miao, Junli Liu
J Mol Cell Biol, Volume 15, Issue 4, April 2023, mjad026, https://doi.org/10.1093/jmcb/mjad026
Abstract | Full Text 

Corrigendum

Corrigendum to ‘microRNA-21a-5p/PDCD4 axis regulates mesenchymal stem cell-induced neuroprotection in acute glaucoma’
Wenru Su, Zuohong Li, Yu Jia, Yingting Zhu, Wenjia Cai, Peixing Wan, Yingying Zhang, Song Guo Zheng, Yehong Zhuo
J Mol Cell Biol, Volume 15, Issue 4, April 2023, mjad028, https://doi.org/10.1093/jmcb/mjad028
Abstract | Full Text 

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Cover: Galectin-9 (Gal-9) potently enhances SARS-CoV-2 replication in airway epithelial cells (AECs), interacting with N-glycans to enhance the binding between viral particles and entry receptors on the target cell surface. Gal-9 accelerates and exacerbates several virus-induced pro-inflammatory programs in AECs that are established signature characteristics of COVID-19 disease and SARS-CoV-2-induced acute respiratory distress syndrome. These findings suggest that Gal-9 is a promising pharmacological target for COVID-19 therapies. See mjad030 by Du et al. for details.