Advanced Search

Submit Online

Volume 15, Issue 10, October 2023

Retrospect

Forty years of HIV research inspires the development of SARS-CoV-2 therapy
Roberto Patarca, William A. Haseltine
J Mol Cell Biol, Volume 15, Issue 10, October 2023, mjad065, https://doi.org/10.1093/jmcb/mjad065
Abstract | Full Text 

Perspective

Targeting dysregulated splicing factors in cancer: lessons learned from RBM10 deficiency
Yongbo Wang, Zefeng Wang
J Mol Cell Biol, Volume 15, Issue 10, October 2023, mjad063, https://doi.org/10.1093/jmcb/mjad063
Abstract | Full Text 

Articles

CBX7 reprograms metabolic flux to protect against meningioma progression by modulating the USP44/c-MYC/LDHA axis
Haixia Cheng, Lingyang Hua, Hailiang Tang, Zhongyuan Bao, Xiupeng Xu, Hongguang Zhu, Shuyang Wang, Zeyidan Jiapaer, Roma Bhatia, Ian F. Dunn, Jiaojiao Deng, Daijun Wang, Shuchen Sun, Shihai Luan, Jing Ji, Qing Xie, Xinyu Yang, Ji Lei, Guoping Li, Xianli Wang, Ye Gong
J Mol Cell Biol, Volume 15, Issue 10, October 2023, mjad057, https://doi.org/10.1093/jmcb/mjad057
Abstract | Full Text 
Sgo1 interacts with CENP-A to guide accurate chromosome segregation in mitosis
Fengge Wu, Hameed Akbar, Chunyue Wang, Xiao Yuan, Zhen Dou, McKay Mullen, Liwen Niu, Liang Zhang, Jianye Zang, Zhikai Wang, Xuebiao Yao, Xiaoyu Song, Xing Liu
J Mol Cell Biol, Volume 15, Issue 10, October 2023, mjad061, https://doi.org/10.1093/jmcb/mjad061
Abstract | Full Text 
The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm
Matthias Hamdorf, Thomas Imhof, Ben Bailey-Elkin, Janina Betz, Sebastian J. Theobald, Alexander Simonis, Veronica Di Cristanziano, Lutz Gieselmann, Felix Dewald, Clara Lehmann, Max Augustin, Florian Klein, Miguel A. Alejandre Alcazar, Robert Rongisch, Mario Fabri, Jan Rybniker, Heike Goebel, Jörg Stetefeld, Bent Brachvogel, Claus Cursiefen, Manuel Koch, Felix Bock
J Mol Cell Biol, Volume 15, Issue 10, October 2023, mjad062, https://doi.org/10.1093/jmcb/mjad062
Abstract | Full Text 
The critical role of BTRC in hepatic steatosis as an ATGL E3 ligase
Weiwei Qi, Zhenzhen Fang, Chuanghua Luo, Honghai Hong, Yanlan Long, Zhiyu Dai, Junxi Liu, Yongcheng Zeng, Ti Zhou, Yong Xia, Xia Yang, Guoquan Gao
J Mol Cell Biol, Volume 15, Issue 10, October 2023, mjad064, https://doi.org/10.1093/jmcb/mjad064
Abstract | Full Text 
Loss of the vitamin D receptor triggers senescence in chronic myeloid leukemia via DDIT4-mediated DNA damage
Yan Xu, Wentao Qi, Chengzu Zheng, Yuan Li, Zhiyuan Lu, Jianmin Guan, Chunhua Lu, Baobing Zhao
J Mol Cell Biol, Volume 15, Issue 10, October 2023, mjad066, https://doi.org/10.1093/jmcb/mjad066
Abstract | Full Text 

< Previous

Next >

Cover: CBX7 expression is downregulated in malignant meningioma, while glycolysis is enhanced in meningioma cells. CBX7 restoration reprograms the metabolic flux from glycolysis to mitochondrial oxidative phosphorylation system (OXPHOS) in meningioma cells, through suppressing USP44 transcription, destabilizing c-MYC protein, and blocking c-MYC-dependent transactivation of LDHA transcription, and thus inhibits meningioma cell proliferation. See mjad057 by Cheng et al. for details.