1State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Life Sciences, Yunnan University, Kunming 650091, China 2Department of Rheumatology and Immunology, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China 3State Key Laboratory of Virology, Wuhan University, Wuhan 430071, China *Correspondence to:Ke-Qin Zhang , Email:kqzhang1@ynu.edu.cn Ying Zhang , Email:ying.zhang84@whu.edu.cn